Animal testing is illogical. Although humans and many other species have similar DNA, and though most organ systems are similar, subtle differences make using animal models to test food, drugs and cosmetics unreliable. Here are just three ways animals don’t react the same as humans.
Rats are known to be more resistant to a certain mushroom toxin than humans. Some mushrooms, notably the Fools webcap, contain a nephrotoxin called orellanine. Rats can eat mushrooms that are deadly to humans.
Feeding a food to animals is not a valid test.
In 2006 a new immune system boosting drug, TGN1412, which had been successfully tested in animals, went to human trials. The subjects were only given the equivalent of 1/500th the safe dose for “non-human primates,” macaques. A single amino acid difference between macaque and human DNA caused violent immune system reactions in humans. Within 90 minutes of the injection, the test subjects suffered searing pain. Within a few hours they suffered multiple organ failure. On a positive note, all the test subjects survived.
Giving a drug to animals is not a valid test.
Dogs and cats don’t usually get poison ivy. Most humans are highly allergic to the active ingredient, urushiol oil. Non-primate species can walk through poison ivy and at most get some irritation.
Applying cosmetics to an animal’s skin is not a valid test.
Fortunately, modern medicine has a number of alternatives to animal tests. One promising technology is Organ Chips, tiny devices about the size of a USB memory stick that contain living human cells.
Lots of drugs don’t make it through the animal trials, but who knows whether the drug companies have thrown away the Magic Bullet simply because it didn’t work on animals?
The Anipal Times 